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ACE2, the Receptor that Enables the Infection by SARS‐CoV‐2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators
(Wiley VCH Verlag, 2020-07)
Angiotensin Converting Enzyme 2 (ACE2) is the human receptor that interacts with the Spike protein of coronaviruses, including the one that produced the 2020 coronavirus pandemic (COVID-19). Thus, ACE2 is a potential target ...
Structural features of coronavirus SARS-CoV-2 spike protein: Targets for vaccination
Various human pathogenic viruses employ envelope glycoproteins for host cell receptor
recognition and binding, membrane fusion and viral entry. The spike (S) glycoprotein of
betacoronavirus SARS-CoV-2 is a homotrimeric ...
Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China,
at the end of 2019, and there are currently no specific antiviral treatments or vaccines
available. SARS-CoV-2 has been shown to use ...
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design
Emergence of coronaviruses poses a threat to global health and economy. The current outbreak
of SARS-CoV-2 has infected more than 28,000,000 people and killed more than 915,000. To date,
there is no treatment for coronavirus ...
Selection of aptamers which binds human ACE-2 (angiotensin converting enzyme) for blocking RBD (receptor-binding domain) of SARS-CoV-2 protein S
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2022)
Accessory toxins of vibriopathogens and their role in epithelial disruption during infection
(Frontiers Media S.A., 2018)
Recent advances in SARS-CoV-2 Spike protein and RBD mutations comparison between new variants Alpha (B.1.1.7, United Kingdom), Beta (B.1.351, South Africa), Gamma (P.1, Brazil) and Delta (B.1.617.2, India)
(2021-09-01)
New variants of SARS-CoV-2 Alpha (B.1.1.7); Beta (B.1.351) Gamma (P.1) and Delta (B.1.617.2) quickly spread in the UK, South Africa, Brazil and India, respectively. To address whether mutations in SARS-CoV-2 RBD spike ...
Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig
(Springer Nature, 2020)
New mass spectrometric assay for angiotensin-converting enzyme 2 activity
(Lippincott Williams & WilkinsPhiladelphiaEUA, 2006)